The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance

Aquaporin 2 (AQP2) mediates the osmotic water permeability of the kidney collecting duct in response to arginine vasopressin (VP) and is essential for body water homeostasis. VP effects on AQP2 occur via long-term alterations in AQP2 abundance and short-term changes in AQP2 localization. Several of...

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Bibliografische Detailangaben

Hauptverfasser:	Sathish K. Murali, Takwa S. Aroankins, Hanne B. Moeller, Robert A. Fenton
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2019-03-01
Schriftenreihe:	Cells
Schlagworte:	water transport NDI aquaporin ubiquitylation post-translational modification
Online-Zugang:	https://www.mdpi.com/2073-4409/8/3/265
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