Lgr5⁺ cells regulate small intestinal morphogenesis before villification

Abstract Lgr5 marks both adult intestinal stem cells and embryonic intestinal stem/progenitor cells. However, the stemness properties and physiological roles of embryonic intestinal Lgr5⁺ cells prior to villification (PVLCs) remain largely unknown. In this study, we show that PVLCs in the embryonic...

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Prif Awduron:	Lianzheng Zhao, Yuchen Xie, Wanlu Song, Yonghui Shen, Huidong Liu, Shiwen Luo, Ye-Guang Chen
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	SpringerOpen 2026-02-01
Cyfres:	Cell Regeneration
Pynciau:	Lgr5 + cells Embryonic small intestine Stemness Morphogenesis Hedgehog signaling
Mynediad Ar-lein:	https://doi.org/10.1186/s13619-026-00284-y
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