Signaling pathway mechanisms in pancreatic ductal adenocarcinoma tumor microenvironment and emerging targeting strategies for improved prognosis

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by a dense desmoplastic stroma and a profoundly immunosuppressive tumor microenvironment (TME). The TME plays a major role in tumor progression, metastasis, and resistance to conventional therapies thr...

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Egile Nagusiak:	Tosin Akinsipe, Caroline O. Odewumi, Lekan Latinwo, Omorose O. Aghimien, Musiliyu A. Musa, Philip O. Igbinoba, Anthony L. Simons, Monica O. Aghimien
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2026-05-01
Saila:	Oncology Reviews
Gaiak:	improved prognosis pancreatic cancer PDAC polymeric nanoparticles signaling pathway targeted delivery
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/or.2026.1814540/full
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