Pharmacometabolomics Study of Sulfamethoxazole and Trimethoprim in Kidney Transplant Recipients: Real-World Metabolism and Urinary Excretion

<b>Background/Objectives</b>: The increased use of antibiotics is raising concerns about environmental contamination and antibiotic resistance, exemplified by the case of cotrimoxazole, a widely prescribed combination of sulfamethoxazole and trimethoprim. After oral administration and absorption, bo...

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Egile Nagusiak:	Marieke A. J. Hof, Hessel de Haan, Stepan Stepanovic, Stephan J. L. Bakker, Eelko Hak, Gérard Hopfgartner, Frank Klont, TransplantLines Investigators
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2025-07-01
Saila:	Metabolites
Gaiak:	humans metabolomics pharmacometabolomics mass spectrometry cohort studies xenobiotics
Sarrera elektronikoa:	https://www.mdpi.com/2218-1989/15/7/473
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