A multi-center study for colorectal cancer early detection in high-risk disease patients using cell-free fragmentomics assay

Abstract Background Early detection of colorectal cancer (CRC) is crucial for improving patient survival. This innovative multi-center study aims to develop a non-invasive blood-based assay using cell-free DNA (cfDNA) fragmentomics to differentiate CRC from advanced colorectal adenomas and non-cance...

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Autors principals:	Jierong Chen, Zhongwen Zheng, Linjie Zhang, Waiting Lam, Qingxin Xie, Lishu Xu, Jing Zhou, Guansheng Zheng, Feng Zhu, Kai Wang, Zejian Lyu, Qinggang Yuan, Ruowei Yang, Xiuxiu Xu, Dongqin Zhu, Lingling Yang, Hua Bao, Deqing Wu, Yong Li, Chao Ding, Bing Gu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-10-01
Col·lecció:	Cancer Cell International
Matèries:	Cell-free DNA fragmentomics Colorectal cancer Advanced colorectal adenoma Early- detection Liquid biopsy
Accés en línia:	https://doi.org/10.1186/s12935-025-03967-9
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