Altered Expression of Vitamin D Metabolism Genes and Circulating MicroRNAs in PBMCs of Patients with Type 1 Diabetes: Their Association with Vitamin D Status and Ongoing Islet Autoimmunity

Background: The immunomodulatory role of 1,25-Dihydroxy vitamin D3 (1,25(OH)2D3) is exerted through its interaction with the vitamin D receptor (VDR) present on pancreatic and immune cells. While a deficiency in vitamin D has been linked to Type 1 Diabetes Mellitus (T1DM), the exact molecular mechan...

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Prif Awduron:	Hakeemah Al-Nakhle, Ihsan Mohsen, Bashir Elnaem, Abdullah Alharbi, Ibtisam Alnakhli, Shareefa Almoarfi, Jameela Fallatah
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2023-10-01
Cyfres:	Non-Coding RNA
Pynciau:	type 1 diabetes mellitus 1,25-Dihydroxy vitamin D PBMCs 1α-hydroxylase (<i>CYP27B1</i>) 24-hydroxylase (<i>CYP24A1</i>) miRNA
Mynediad Ar-lein:	https://www.mdpi.com/2311-553X/9/5/60
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!