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Screening of Fenofibrate-Simvastatin Solid Dispersions in the Development of Fixed-Dose Formulations for the Treatment of Lipid Disorders

The combination of statins and fibrates in the treatment of lipid abnormalities effectively regulates individual lipid fraction levels. In this study, the screening and assessment of the physicochemical properties of simvastatin-fenofibrate solid dispersions were performed. Fenofibrate and simvastat...

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Principais autores: Agata Górniak, Hanna Czapor-Irzabek, Adrianna Złocińska, Agnieszka Gawin-Mikołajewicz, Bożena Karolewicz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-02-01
coleção:Pharmaceutics
Assuntos:
simvastatin
fenofibrate
solid dispersion
eutectic
dissolution improvement
dyslipidemia
Acesso em linha:https://www.mdpi.com/1999-4923/15/2/603
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