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ICAM-1-LFA-1 Dependent CD8+ T-Lymphocyte Aggregation in Tumor Tissue Prevents Recirculation to Draining Lymph Nodes

The quantity of T-lymphocytes reaching the draining lymph nodes from tumors is likely important to mount effective distant responses and for the establishment of long term systemic memory. Looking into mechanisms behind lymphocyte egress, we directed our attention to leukocyte adhesion mechanisms in...

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Autori principali: Alba Yanguas, Saray Garasa, Álvaro Teijeira, Cristina Aubá, Ignacio Melero, Ana Rouzaut
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018-09-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/article/10.3389/fimmu.2018.02084/full
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