Genetic variants regulating the immune response improve the prediction of COVID-19 severity provided by clinical variables

Abstract The characteristics of the host are crucial in the final outcome of COVID-19. Herein, the influence of genetic and clinical variants in COVID-19 severity was investigated in a total of 1350 patients. Twenty-one single nucleotide polymorphisms of genes involved in SARS-CoV-2 sensing as Toll-...

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Main Authors:	Pablo Delgado-Wicke, Sara Fernández de Córdoba-Oñate, Emilia Roy-Vallejo, Estíbaliz Alegría-Carrasco, Diego A. Rodríguez-Serrano, Amalia Lamana, Nuria Montes, Ana Nicolao-Gómez, Rosa Carracedo-Rodríguez, Ana Marcos-Jiménez, Paula Díaz-Fernández, José M. Galván-Román, Laura Rabes-Rodríguez, Marta Sanz-Alba, Jesús Álvarez-Rodríguez, Almudena Villa-Martí, Carlos Rodríguez-Franco, Gonzalo Villapalos-García, Pablo Zubiaur, Francisco Abad-Santos, Ignacio de los Santos, Rosa P. Gomariz, Rosario García-Vicuña, Cecilia Muñoz-Calleja, Isidoro González-Álvaro, Elena Fernández-Ruiz, PREDINMUN-COVID Group
Format:	Artigo
Language:	Inglês
Published:	Nature Portfolio 2024-09-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-024-71476-2
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