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Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors

Considering the unrecognised physio-pathological role of human carbonic anhydrase III (hCA III), a structure-based drug design was set up to identify the first-in-class potent and selective inhibitors of this neglected isoform. hCA III targeting was planned considering a unique feature of its active...

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Detaylı Bibliyografya
Asıl Yazarlar: Simone Giovannuzzi, Alessandro Bonardi, Paola Gratteri, Alessio Nocentini, Claudiu T. Supuran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2023-12-01
Seri Bilgileri:Journal of Enzyme Inhibition and Medicinal Chemistry
Konular:
Online Erişim:https://www.tandfonline.com/doi/10.1080/14756366.2023.2202360
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