Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in Caenorhabditis elegans model of Huntington’s disease

Yixuan Zeng,1,2,* Wenyuan Guo,1,* Guangqing Xu,3 Qinmei Wang,4 Luyang Feng,1,2 Simei Long,1 Fengyin Liang,1 Yi Huang,1 Xilin Lu,1 Shichang Li,5 Jiebin Zhou,5 Jean-Marc Burgunder,6 Jiyan Pang,5 Zhong Pei1,2 1Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, G...

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Autors principals:	Zeng YX, Guo WY, Xu GQ, Wang QM, Feng LY, Long SM, Liang FY, Huang Y, Lu XL, Li SC, Zhou JB, Burgunder JM, Pang JY, Pei Z
Format:	Artigo
Idioma:	Inglês
Publicat:	Dove Medical Press 2016-04-01
Col·lecció:	Drug Design, Development and Therapy
Matèries:	Huntington disease mutant Huntingtin Xyloketal derivatives Caenorhabdatis elegans Protein misfolding Molecular target
Accés en línia:	https://www.dovepress.com/xyloketal-derived-small-molecules-show-protective-effect-by-decreasing-peer-reviewed-article-DDDT
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