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Development of new HPLC method for identification of metabolic degradation of N-pyrrolylhydrazide hydrazones with determined MAO- B activity in cellular cultures

In this research, a new rapid PR- HPLC method was developed for the determination of metabolites in isolated rat hapatocytes. The chromatographic parameters, including the stationary and mobile phases, outlet pressure, temperature and flow rate, were optimized. The method identified two initial from...

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Detalhes bibliográficos
Principais autores: Alexandrina Mateeva, Lily Peikova, Magdalena Kondeva-Burdina, Maya Georgieva
Formato: Artigo
Idioma:Inglês
Publicado em: Pensoft Publishers 2022-01-01
Colecção:Pharmacia
Acesso em linha:https://pharmacia.pensoft.net/article/78417/download/pdf/
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