Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation

The human cytomegalovirus (HCMV) US12 family consists of ten sequentially arranged genes (US12-21) with poorly characterized function. We now identify novel natural killer (NK) cell evasion functions for four members: US12, US14, US18 and US20. Using a systematic multiplexed proteomics approach to q...

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Autores principales:	Ceri A Fielding, Michael P Weekes, Luis V Nobre, Eva Ruckova, Gavin S Wilkie, Joao A Paulo, Chiwen Chang, Nicolás M Suárez, James A Davies, Robin Antrobus, Richard J Stanton, Rebecca J Aicheler, Hester Nichols, Borek Vojtesek, John Trowsdale, Andrew J Davison, Steven P Gygi, Peter Tomasec, Paul J Lehner, Gavin W G Wilkinson
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2017-02-01
Colección:	eLife
Materias:	cytomegalovirus human immune evasion natural killer cell
Acceso en línea:	https://elifesciences.org/articles/22206
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