Lineage tracing for multiple lung cancer by spatiotemporal heterogeneity using a multi-omics analysis method integrating genomic, transcriptomic, and immune-related features

IntroductionThe distinction between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IPM) holds clinical significance in staging, therapeutic intervention, and prognosis assessment for multiple lung cancer. Lineage tracing by clinicopathologic features alone remains a clinical chal...

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Hlavní autoři:	Yijun Song, Jiebai Zhou, Xiaotian Zhao, Yong Zhang, Xiaobo Xu, Donghui Zhang, Jiaohui Pang, Hairong Bao, Yuan Ji, Mengna Zhan, Yulin Wang, Qiuxiang Ou, Jie Hu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-09-01
Edice:	Frontiers in Oncology
Témata:	lineage tracing multiple lung cancer spatiotemporal heterogeneity multi-omics analysis method multiple primary lung cancer (MPLC) intrapulmonary metastasis (IPM)
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1237308/full
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