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Nivolumab and ipilimumab population pharmacokinetics in support of pediatric dose recommendations—Going beyond the body‐size effect

Abstract Body size has historically been considered the primary source of difference in the pharmacokinetics (PKs) of monoclonal antibodies (mAbs) between children aged greater than or equal to 2 years and adults. The contribution of age‐associated differences (e.g., ontogeny) beyond body‐size diffe...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Zheyi Hu, Sihang Liu, Yue Zhao, Shengnan Du, Lora Hamuro, Jun Shen, Amit Roy, Li Zhu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Wiley 2024-03-01
Rangatū:CPT: Pharmacometrics & Systems Pharmacology
Urunga tuihono:https://doi.org/10.1002/psp4.13098
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