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An update to the Monro–Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke

Abstract High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury or death following severe stroke. Compensatory mechanisms include reduced cerebral blood and cerebrospinal fluid volumes, but these often fail to prevent raised ICP. Serendipitous observations in i...

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Principais autores: Anna C. J. Kalisvaart, Cassandra M. Wilkinson, Sherry Gu, Tiffany F. C. Kung, Jerome Yager, Ian R. Winship, Frank K. H. van Landeghem, Frederick Colbourne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2020-12-01
Colecção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-020-78880-4
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