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In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, distinctively characterized by senile plaques, neurofibrillary tangles, and synaptic loss, finally resulting in neuronal death. β-Site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cholinesterases ha...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Seungeun Lee, Kumju Youn, GyuTae Lim, Jinhyuk Lee, Mira Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-06-01
Schriftenreihe:Molecules
Schlagworte:
Alzheimer’s disease
BACE1
cholinesterases
in silico docking
citrus flavanones
hesperidin
Online-Zugang:http://www.mdpi.com/1420-3049/23/7/1509
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