Single-cell insights: pioneering an integrated atlas of chromatin accessibility and transcriptomic landscapes in diabetic cardiomyopathy

Abstract Background Diabetic cardiomyopathy (DCM) poses a growing health threat, elevating heart failure risk in diabetic individuals. Understanding DCM is crucial, with fibroblasts and endothelial cells playing pivotal roles in driving myocardial fibrosis and contributing to cardiac dysfunction. Ad...

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Auteurs principaux:	Qiang Su, Wanzhong Huang, Yuan Huang, Rixin Dai, Chen Chang, Qiu-Yan Li, Hao Liu, Zhenhao Li, Yuxiang Zhao, Qiang Wu, Di-Guang Pan
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2024-04-01
Collection:	Cardiovascular Diabetology
Sujets:	DCM scRNA-seq scATAC-seq Cardiomyocytes Fibroblasts Endothelial
Accès en ligne:	https://doi.org/10.1186/s12933-024-02233-y
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