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Age at Menarche and Risk of Multiple Sclerosis: Current Progress From Epidemiological Investigations

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disorder of the brain and spinal cord in which focal lymphocytic infiltration leads to the damage of myelin and axons. As a multi-factorial complex trait, both genetic background and environmental factors are involved in MS etiology. The d...

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Principais autores: Xia Jiang, Tomas Olsson, Lars Alfredsson
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-11-01
Serier:Frontiers in Immunology
Fag:
puberty
age at menarche
hormone
multiple sclerosis
population-based
epidemiology
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2018.02600/full
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