Exploring the impact of dexamethasone on gene regulation in myeloma cells

The study uncovers epigenomic changes associated with dexamethasone response heterogeneity in myeloma cells, revealing rewired promoter–enhancer interactions and DNA loop stabilization. Among glucocorticoids (GCs), dexamethasone (Dex) is widely used in treatment of multiple myelomas. However, despit...

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Autori principali:	Victor Bessonneau-Gaborit, Jonathan Cruard, Catherine Guerin-Charbonnel, Jennifer Derrien, Jean-Baptiste Alberge, Elise Douillard, Magali Devic, Sophie Deshayes, Loïc Campion, Frank Westermann, Phillipe Moreau, Carl Herrmann, Jérémie Bourdon, Florence Magrangeas, Stéphane Minvielle
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Life Science Alliance LLC 2023-09-01
Serie:	Life Science Alliance
Accesso online:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302195
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