Lithium carbonate and coenzyme Q10 reduce cell death in a cell model of Machado-Joseph disease

Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by expansion of the polyglutamine domain of the ataxin-3 (ATX3) protein. MJD/SCA3 is the most frequent autosomal dominant ataxia in many countries. The mechanism underlying...

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Autores principales:	C.M. Lopes-Ramos, T.C. Pereira, D.B. Dogini, R. Gilioli, I. Lopes-Cendes
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Associação Brasileira de Divulgação Científica
Colección:	Brazilian Journal of Medical and Biological Research
Materias:	Machado-Joseph disease Spinocerebellar ataxia type 3 Lithium carbonate Coenzyme Q10 Drug treatment
Acceso en línea:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001200601&lng=en&tlng=en
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