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Mesoporous Bioactive Glasses Incorporated into an Injectable Thermosensitive Hydrogel for Sustained Co-Release of Sr<sup>2+</sup> Ions and <i>N</i>-Acetylcysteine

An injectable delivery platform for promoting delayed bone healing has been developed by combining a thermosensitive polyurethane-based hydrogel with strontium-substituted mesoporous bioactive glasses (MBG_Sr) for the long-term and localized co-delivery of pro-osteogenic Sr<sup>2+</sup> ions and an...

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Principais autores: Carlotta Pontremoli, Monica Boffito, Rossella Laurano, Giorgio Iviglia, Elisa Torre, Clara Cassinelli, Marco Morra, Gianluca Ciardelli, Chiara Vitale-Brovarone, Sonia Fiorilli
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-09-01
Serier:Pharmaceutics
Fag:
mesoporous bioactive glasses
injectable hydrogels
<i>N</i>-acetylcysteine
strontium ions
co-release
delayed bone regeneration
Online adgang:https://www.mdpi.com/1999-4923/14/9/1890
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