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Single-cell transcriptomics reveals tumor microenvironment remodeling in hepatocellular carcinoma with varying tumor subclonal complexity

IntroductionThe complexity of tumor cell subclonal structure has been extensively investigated in hepatocellular carcinoma. However, the role of subclonal complexity in reshaping the tumor microenvironment (TME) remains poorly understood.MethodsWe integrated single-cell transcriptome sequencing data...

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書誌詳細
主要な著者: Jian Shi, Yanru Zhang, Lixia Xu, Fang Wang
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2024-08-01
シリーズ:Frontiers in Genetics
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fgene.2024.1467682/full
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