Combined minimally invasive vagal cranial nerve and trigeminocervical complex peripheral nerve stimulation produces prolonged improvement of severe painful peripheral neuropathy and hyperglycemia in type 2 diabetes

IntroductionDiabetic Peripheral Neuropathy (DPN), a debilitating complication of type 2 diabetes mellitus (T2DM), stems from bioenergetic failure and reduced vascular endothelial growth factor-A expression (VEGF-A), persisting despite optimal glycemic control. The meteoric rise of “diabesity”—the co...

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Bibliografski detalji

Glavni autori:	Peter S. Staats, Alyssa Staats, Brittny Mikhaiel, Jason Chen, Eric Azabou, Claire-Marie Rangon
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-08-01
Serija:	Frontiers in Neuroscience
Teme:	vagus nerve trigeminocervical complex minimally invasive stimulation closed-loop neuromodulation type 2 diabetes diabetic peripheral neuropathy
Online pristup:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1644961/full
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