Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo?
Background: Diabetes always involves variable degrees of β-cell demise and malfunction leading to insufficient insulin secretion. Besides clinical investigations, many research projects used rodent islets to study various facets of β-cell pathophysiology. Their important contributions laid the found...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021-06-01
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| coleção: | Molecular Metabolism |
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| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2212877821000521 |
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