Spatial single cell transcriptomic analysis informs tumor developmental hierarchy of DICER1 syndrome related sarcoma

Abstract DICER1-related tumor predisposition (DRTP), also known as DICER1 syndrome, encompasses a spectrum of malignancies mainly in children and young adults. Most are sarcomas, exhibiting histological and molecular similarities regardless of their anatomical origins, and only express the RNase III...

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Autores principales:	Felix K. F. Kommoss, Joyce Yu Han Zhang, Branden J. Lynch, Shary Yuting Chen, Janine Senz, Yana Moscovitz, Lesley A. Hill, Ding Ma, R. Wilder Scott, Jonathan Bush, Kenneth S. Chen, Andrew Roth, Andreas von Deimling, William D. Foulkes, Gregg B. Morin, T. Michael Underhill, Yemin Wang, David G. Huntsman
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2026-03-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-026-70971-6
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