MIWI2 as an Effector of DNA Methylation and Gene Silencing in Embryonic Male Germ Cells
During the development of mammalian embryonic germ cells, global demethylation and de novo DNA methylation take place. In mouse embryonic germ cells, two PIWI family proteins, MILI and MIWI2, are essential for the de novo DNA methylation of retrotransposons, presumably through PIWI-interacting RNAs...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016-09-01
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| Schriftenreihe: | Cell Reports |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2211124716310919 |
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