Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial

<i>Background and Objectives</i>: Cardiovascular (CV) risk is elevated in rheumatoid arthritis (RA). RA patient plasma causes pro-atherogenic derangements in cholesterol transport leading to macrophage foam cell formation (FCF). The TARGET randomized clinical trial compares CV benefits of 2 RA drug...

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Hauptverfasser:	Saba Ahmed, Justin Konig, Lora J. Kasselman, Heather A. Renna, Joshua De Leon, Steven E. Carsons, Allison B. Reiss
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-09-01
Schriftenreihe:	Medicina
Schlagworte:	atherosclerosis cholesterol hydoxychloroquine macrophage scavenger receptors
Online-Zugang:	https://www.mdpi.com/1648-9144/58/9/1287
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