The secreted proteases Aur, ScpA, SspA and SspB suppress the virulence of Staphylococcus aureus USA300 by shaping the extracellular proteome

Surface-located and secreted virulence factors of the Gram-positive bacterial pathogen Staphylococcus aureus are key drivers for infection of the human host. Proteolytic enzymes may contribute to virulence by breaking primary barriers and host immune defenses. Therefore, the objective of our study w...

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Detalhes bibliográficos

Principais autores:	Xiaofang Li, Sandra Maaß, Borja Ferrero-Bordera, Zhichao Zhang, Min Wang, Eric Sietsema, Lei Liu, Madeleine Divinagracia, Jan Maarten van Dijl, Girbe Buist
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2025-12-01
coleção:	Virulence
Assuntos:	Staphylococcus aureus virulence proteases peptidoglycan hydrolase cell lysis
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/21505594.2025.2514790
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