Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma

Tumor suppression by the extracts of Azadirachta indica (neem) works via anti-proliferation, cell cycle arrest, and apoptosis, demonstrated previously using cancer cell lines and live animal models. However, very little is known about the molecular targets and pathways that neem extracts and their a...

Cijeli opis

Bibliografski detalji

Glavni autori:	Neeraja M. Krishnan, Hiroto Katoh, Vinayak Palve, Manisha Pareek, Reiko Sato, Shumpei Ishikawa, Binay Panda
Format:	Artigo
Jezik:	Inglês
Izdano:	PeerJ Inc. 2019-03-01
Serija:	PeerJ
Teme:	Drug target Pooled shRNA screen Neem Gene expression HSF-1 TGF-β
Online pristup:	https://peerj.com/articles/6464.pdf
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!