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7-Chloroquinolinehydrazones as First-in-Class Anticancer Experimental Drugs in the NCI-60 Screen among Different Investigated Series of Aryl, Quinoline, Pyridine, Benzothiazole and Imidazolehydrazones

In the context of a continuously increasing global cancer risk, the search for new effective and affordable anticancer drugs remains a constant demand. This study describes chemical experimental drugs able to destroy cancer cells by arresting their growth. New hydrazones with quinoline, pyridine, be...

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Principais autores: Georgiana Negru (Apostol), Alina Ghinet, Elena Bîcu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-05-01
Serier:Pharmaceuticals
Fag:
hydrazone
7-chloroquinoline
NCI panel
antitumor
pharmacomodulation
SAR
Online adgang:https://www.mdpi.com/1424-8247/16/5/691
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