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Lipophilicity and Related Molecular Properties as Determinants of Pharmacokinetic Behaviour

This minireview presents some recent work, mainly from the authors' laboratory, aimed at improving the interpretability and predictivity of structure-pharmacokinetic relationships. The first part of the text discusses the intermolecular forces and intramolecular interactions encoded in lip...

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Bibliografische gegevens
Hoofdauteurs: Bernard Testa, Giulia Caron, Patrizia Crivori, Sébastien Rey, Marianne Reist, Pierre Alain Carrupt
Formaat: Artigo
Taal:Alemão
Gepubliceerd in: Swiss Chemical Society 2000-11-01
Reeks:CHIMIA
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Online toegang:https://chimia.ch/chimia/article/view/3310
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