VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of bla NDM-5 in zoonotic bacteria

Abstract IncX3 plasmids carrying the New Delhi metallo-β-lactamase-encoding gene, bla NDM-5, are rapidly spreading globally in both humans and animals. Given that carbapenems are listed on the WHO AWaRe watch group and are prohibited for use in animals, the drivers for the successful dissemination o...

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Auteurs principaux:	Tengfei Ma, Ning Xie, Yuan Gao, Jiani Fu, Chun E. Tan, Qiu E. Yang, Shaolin Wang, Zhangqi Shen, Quanjiang Ji, Julian Parkhill, Congming Wu, Yang Wang, Timothy R. Walsh, Jianzhong Shen
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2024-06-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-024-49800-1
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