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Kinesin-7 CENP-E in tumorigenesis: Chromosome instability, spindle assembly checkpoint, and applications

Kinesin motors are a large family of molecular motors that walk along microtubules to fulfill many roles in intracellular transport, microtubule organization, and chromosome alignment. Kinesin-7 CENP-E (Centromere protein E) is a chromosome scaffold-associated protein that is located in the corona l...

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Principais autores: Yu-Hao Yang, Ya-Lan Wei, Zhen-Yu She
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-03-01
coleção:Frontiers in Molecular Biosciences
Assuntos:
kinesin
CENP-E
chromosome instability
cancer
aneuploidy
tumorigenesis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1366113/full
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