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piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm

In Drosophila embryos, Piwi-interacting RNAs (piRNAs) loaded into the PIWI protein Aubergine target and destabilize maternal mRNAs. Here, the authors provide evidence that piRNAs and Aubergine cooperate with the Wispy poly(A) polymerase to stabilize these mRNAs in the germ plasm.

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Bibliografiske detaljer
Principais autores: Jérémy Dufourt, Gwénaëlle Bontonou, Aymeric Chartier, Camille Jahan, Anne-Cécile Meunier, Stéphanie Pierson, Paul F. Harrison, Catherine Papin, Traude H. Beilharz, Martine Simonelig
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2017-11-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-017-01431-5
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