Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes

Previous studies had shown that the integration of genome wide expression profiles, in metabolic tissues, with genetic and phenotypic variance, provided valuable insight into the underlying molecular mechanisms. We used RNA-Seq to characterize hypothalamic transcriptome in 99 inbred strains of mice...

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Autors principals:	Yehudit Hasin-Brumshtein, Arshad H Khan, Farhad Hormozdiari, Calvin Pan, Brian W Parks, Vladislav A Petyuk, Paul D Piehowski, Anneke Brümmer, Matteo Pellegrini, Xinshu Xiao, Eleazar Eskin, Richard D Smith, Aldons J Lusis, Desmond J Smith
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2016-09-01
Col·lecció:	eLife
Matèries:	RNA-Seq trans-eQTL hypothalamus high fat diet obesity eQTL
Accés en línia:	https://elifesciences.org/articles/15614
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