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The functions and clinical significance of circRNAs in hematological malignancies

Abstract With covalently closed circular structures, circular RNAs (circRNAs) were once misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved, and tissue-specific, circRNAs are recently identified as a type of regulatory RNAs. CircRNAs bind to certain miRNAs or pro...

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Principais autores: Xiangxiang Zhou, Linquan Zhan, Kai Huang, Xin Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-10-01
Serier:Journal of Hematology & Oncology
Fag:
Circular RNAs
Hematological malignancies
Tumorigenesis
Drug-resistance
Biomarker
Online adgang:http://link.springer.com/article/10.1186/s13045-020-00976-1
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