Scaffold Hopping of α-Rubromycin Enables Direct Access to FDA-Approved Cromoglicic Acid as a SARS-CoV-2 M^Pro Inhibitor

The COVID-19 pandemic is still active around the globe despite the newly introduced vaccines. Hence, finding effective medications or repurposing available ones could offer great help during this serious situation. During our anti-COVID-19 investigation of microbial natural products (MNPs), we came...

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Principais autores:	Hani A. Alhadrami, Ahmed M. Sayed, Heba Al-Khatabi, Nabil A. Alhakamy, Mostafa E. Rateb
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-06-01
Series:	Pharmaceuticals
Assuntos:	COVID-19 <i>Streptomyces collinus</i> α-rubromycin in silico M<sup>Pro</sup> cromolyn
Acceso en liña:	https://www.mdpi.com/1424-8247/14/6/541
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