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Characterization of serotonin-induced inhibition of excitatory synaptic transmission in the anterior cingulate cortex

Abstract Excitatory synaptic transmission in central synapses is modulated by serotonin (5-HT). The anterior cingulate cortex (ACC) is an important cortical region for pain perception and emotion. ACC neurons receive innervation of projecting serotonergic nerve terminals from raphe nuclei, but the p...

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Main Authors: Zhen Tian, Manabu Yamanaka, Matteo Bernabucci, Ming-gao Zhao, Min Zhuo
Format: Artigo
Language:Inglês
Published: BMC 2017-06-01
Series:Molecular Brain
Subjects:
Anterior cingulate cortex
Serotonin
Excitatory postsynaptic currents
Adenylyl cyclase
Glutamatergic neurotransmission
Online Access:http://link.springer.com/article/10.1186/s13041-017-0303-1
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