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An efficient and scalable data analysis solution for automated electrophysiology platforms

Ion channels are drug targets for neurologic, cardiac, and immunologic diseases. Many disease-associated mutations and drugs modulate voltage-gated ion channel activation and inactivation, suggesting that characterizing state-dependent effects of test compounds at an early stage of drug development...

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Autors principals: Tianbo Li, Martin Ginkel, Ada X. Yee, Leigh Foster, Jun Chen, Stephan Heyse, Stephan Steigele
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2022-06-01
Col·lecció:SLAS Discovery
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2472555221000162
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