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Nobiletin Ameliorates Aβ1–42‐Induced Cognitive Disorder and Mitochondrial Dysfunction via Targeting the Key Circadian Regulator Bmal1

ABSTRACT Alzheimer‘s disease is a neurodegenerative disease ​​characterized by​​ cognitive impairment and memory loss. The excessive accumulation of amyloid beta (Aβ) in brain is one of the pathogenesis of Alzheimer's disease. Nobiletin (NOB) is a kind of polymethoxy flavone that exists in some citr...

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Autori principali: Huajing Gao, Qinglin Qu, Ning Wang, Xue Gao, Peihua Li, Yanquan Mou, Xiangrui Kong, Yannan Chen, Dapeng Li, Xintong Tan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2026-01-01
Serie:Food Safety and Health
Soggetti:
Alzheimer's disease
Bmal1
circadian rhythm
mitochondrial
nobiletin
Accesso online:https://doi.org/10.1002/fsh3.70040
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