Calpain-1 Potentiates Periodontal Regeneration via PHLPP1-ERK-Driven Osteogenesis in Periodontal Ligament Stem Cells

Objectives: In recent years, human periodontal ligament stem cells (hPDLSCs) are considered a promising seed cell source for bone tissue engineering, offering a prospective treatment for periodontal bone defects. The osteogenic differentiation of hPDLSCs is a critical process in bone tissue engineer...

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Ngā kaituhi matua:	Yuejia Li, Bin Yang, Ziyi Mei, Pingmeng Deng, Tiwei Fu, Jie Li
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2026-02-01
Rangatū:	International Dental Journal
Ngā marau:	Bone tissue engineering Calpain 1 ERK1/2 hPDLSCs Osteogenic differentiation
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S0020653925085922
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!