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Characterization and preliminary cytotoxic effects of pomegranate peel extract-loaded nanoparticles on HepG2 cells

Abstract Punica granatum (pomegranate) peel is recognized for its rich phytochemical profile and traditional use in medicinal applications, making it a promising source of anticancer agents. In this study, an aqueous pomegranate peel extract (PPE) was prepared and encapsulated into chitosan nanopart...

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Main Authors: Reem Ahmed Mahmoud, Hamdy Hassanine, Ali Ashry, Hossam El-Din M. Omar, Walaa M. El-Sherif, Metwally Kotb Mahfouz
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2026-03-01
Series:Scientific Reports
Subjects:
Punica granatum
Nanoencapsulation
Cytotoxicity
MTT assay
GC analysis
HepG2 cells
Online Access:https://doi.org/10.1038/s41598-026-36063-7
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