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Systematic Review of Efficacy and Safety of Avacopan in Real-World Clinical Practice

Introduction: Avacopan, a complement 5a receptor (C5aR) antagonist, is a therapeutic option for patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), and is used as a steroid-sparing agent. The efficacy and safety of avacopan were established in the pivotal phase III...

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Main Authors: Ilay Berke, Felix Keller, Clemens Untersulzner, Jae Il Shin, Peong Gang Park, Sarah Soyeon Oh, Jasper Callemeyn, Andreas Kronbichler
Format: Artigo
Language:Inglês
Published: Elsevier 2026-04-01
Series:Kidney International Reports
Subjects:
ANCA
avacopan
complement
treatment
vasculitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925007715
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