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Immunopeptidome of hepatocytes isolated from patients with HBV infection and hepatocellular carcinoma

Background & Aims: Antigen-specific immunotherapy is a promising strategy to treat HBV infection and hepatocellular carcinoma (HCC). To facilitate killing of malignant and/or infected hepatocytes, it is vital to know which T cell targets are presented by human leucocyte antigen (HLA)-I complexes...

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Hoofdauteurs: Monique T.A. de Beijer, Karel Bezstarosti, Robbie Luijten, Wouter A.S. Doff, Patrick P.C. Boor, Roel F.A. Pieterman, Rachid Bouzid, Paula J. Biesta, Jan N.M. Ijzermans, Michail Doukas, Robert A. de Man, Andrea M. Woltman, Jeroen A.A. Demmers, Sonja I. Buschow
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2022-11-01
Reeks:JHEP Reports
Onderwerpen:
Antigen presentation
Liver cancer
T cell epitope
HLA
MHC
Peptidome
Online toegang:http://www.sciencedirect.com/science/article/pii/S2589555922001483
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