Sustained Surface ICAM-1 Expression and Transient PDGF-B Production by Phorbol Myristate Acetate-Activated THP-1 Cells Harboring Blau Syndrome-Associated <em>NOD2</em> Mutations

Objectives: Blau syndrome is a distinct class of autoinflammatory syndrome presenting with early-onset systemic granulomatosis. Blau syndrome-causing <i>NOD2</i> mutations located in the central nucleotide-oligomerization domain induce ligand-independent basal NF-κB activation in an in vitro reporte...

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Principais autores:	Mizuho Nishiyama, Hong-jin Li, Ikuo Okafuji, Akihiko Fujisawa, Mizue Ehara, Naotomo Kambe, Fukumi Furukawa, Nobuo Kanazawa
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-04-01
Series:	Children
Assuntos:	Blau syndrome <i>NOD2</i> mutation ICAM-1 PDGF-B
Acceso en liña:	https://www.mdpi.com/2227-9067/8/5/335
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