Nuclear CK1δ as a critical determinant of PER:CRY complex dynamics and circadian period
The mammalian circadian clock is governed by a feedback loop in which the transcription activator CLOCK:BMAL1 induces expression of its inhibitors, PERs and CRYs, which form a complex with CK1δ, the main circadian kinase. However, the spatiotemporal dynamics of this feedback loop and the precise rol...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications Ltd
2026-06-01
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| Serija: | eLife |
| Teme: | |
| Online dostop: | https://elifesciences.org/articles/110786 |
| Oznake: |
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