A Role for the VPS Retromer in <italic toggle="yes">Brucella</italic> Intracellular Replication Revealed by Genomewide siRNA Screening

ABSTRACT Brucella, the agent causing brucellosis, is a major zoonotic pathogen with worldwide distribution. Brucella resides and replicates inside infected host cells in membrane-bound compartments called Brucella-containing vacuoles (BCVs). Following uptake, Brucella resides in endosomal BCVs (eBCV...

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Bibliografische Detailangaben

Hauptverfasser:	Alain Casanova, Shyan Huey Low, Maxime Québatte, Jaroslaw Sedzicki, Therese Tschon, Maren Ketterer, Kevin Smith, Mario Emmenlauer, Houchaima Ben-Tekaya, Christoph Dehio
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2019-06-01
Schriftenreihe:	mSphere
Schlagworte:	Brucella RAB7A VPS retromer VPS26 VPS35 replicative niche
Online-Zugang:	https://journals.asm.org/doi/10.1128/mSphere.00380-19
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