Modulation of dorsal hippocampal SK2 channels regulates morphine-enhanced neuronal oscillations and morphine-induced contextual memory encoding and retrieval

Abstract Persistent maladaptive drug-context associations are a key component of relapse vulnerability and pose a major obstacle in treating opioid use disorder. Although the dorsal hippocampus (dHPC) is critical for contextual memory formation, the synaptic mechanisms by which opioids alter hippoca...

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Detalhes bibliográficos

Principais autores:	Khairunisa Mohamad Ibrahim, Dominika J. Burek, Azra Zec, Olayinka Idowu, Will W. Post, Alice Zheng, Basma Daham, Justin D. Meyer, Sidney Williams, Nicolas Massaly, Jose A. Morón
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-11-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-025-24819-6
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