The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice

Red blood cell (RBC) transfusions are essential for patients with hematological disorders and bone marrow failure syndromes. Despite ABO matching, RBC transfusions can lead to production of alloantibodies against “minor” blood group antigens. Non-ABO alloimmunization is a leading cause of transfusio...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	David R. Gibb, Samuele Calabro, Dong Liu, Christopher A. Tormey, Steven L. Spitalnik, James C. Zimring, Jeanne E. Hendrickson, Eldad A. Hod, Stephanie C. Eisenbarth
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2016-07-01
Schriftenreihe:	EBioMedicine
Schlagworte:	NLRP3 Inflammasome Alloimmunization Conventional dendritic cells (cDCs) Red blood cell (RBC) storage
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2352396416302523
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